Endocrine Abstracts

In 2003, a 60-year-old man presented to our unit non-specifically unwell. Thyroid function tests (TFTs) demonstrated an elevated fT4 of 50 pmol/l (reference range 10–22 pmol/l)), T3 8.8 pmol/l (reference range 3.1–6.8 pmol/l) and TSH of 10.3 mU/l (reference range 0.5–4.5 mU/l)). Following appropriate investigations, a TSHoma was confirmed. MRI of the Pituitary confirmed the finding of a macroadenoma and the patient underwent pituitary decom...

We report a case of severe postradiation encephalitis presenting 6 months following pituitary radiotherapy for pituitary adenoma. Our patient (78 years old female) was diagnosed with non-functioning pituitary ademona compromising the optic chiasm in 1999 at the age of 66 years. She underwent transphenoideal decompression in 2000. Over the next 8 years there was slow re-growth of the pituitary adenoma and by 2008 it was causing optic chiasm compression. At this stage, the patie...

A 29-year-old lady with known Addison’s disease and hypothyroidism was admitted with a history of increasing lethargy and dizziness for 2 weeks. At the time of admission she was on (and compliant with) Hydrocortisone 20 mg twice daily, Fludrocortisone 100 mcg once daily and Thyroxine 150 mcg once daily. On the day of admission her BP was 128/92 mmHg with no postural drop. Her electrolytes were normal, however an early morning cortisol measured 28 mmol/l. She was treated w...